Malignant fibrous histiocytoma at the site of a total hip replacement: review of the literature and case report

Skeletal Radiol. 1997 Sep;26(9):559-63. doi: 10.1007/s002560050287.


Tumors developing in association with metallic implants are being reported with increasing frequency in the orthopedic literature. The authors report the tenth case of malignant fibrous histiocytoma associated with a total hip replacement. The diagnosis was made during an evaluation for rapid radiographic osteolysis surrounding the femoral component detected less than 1 year after revision of a hemiarthroplasty to a total hip replacement. The short latency period and aggressiveness of this tumor mimicking rapid osteolysis prompted a review of the literature, etiology and significance of implant-associated malignant fibrous histiocytoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Arthroplasty, Replacement, Hip / adverse effects*
  • Fatal Outcome
  • Female
  • Femoral Neck Fractures / surgery
  • Histiocytoma, Benign Fibrous / diagnosis*
  • Histiocytoma, Benign Fibrous / etiology
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Reoperation
  • Soft Tissue Neoplasms / diagnosis*
  • Soft Tissue Neoplasms / etiology
  • Tomography, X-Ray Computed