A male with fetal valproate syndrome and autism

Dev Med Child Neurol. 1997 Sep;39(9):632-4. doi: 10.1111/j.1469-8749.1997.tb07500.x.


Fetal valproate syndrome (FVS) is characterized by minor craniofacial anomalies, major organ malformations, and developmental delay. We report on a patient who has a clinical phenotype compatible with both FVS and autism. The presence of an autistic disorder in a previously reported case of FVS and similar findings in our patient suggest that a relation between this known teratogen and autism may exist.

Publication types

  • Case Reports

MeSH terms

  • Anticonvulsants / adverse effects*
  • Audiology
  • Autistic Disorder / chemically induced*
  • Child, Preschool
  • Developmental Disabilities / chemically induced*
  • Female
  • Humans
  • Language Disorders / chemically induced
  • Language Disorders / diagnosis
  • Male
  • Neuropsychological Tests
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Valproic Acid / adverse effects*


  • Anticonvulsants
  • Valproic Acid