Regional cerebral blood flow changes related to affective speech presentation in persistent vegetative state

Clin Neurol Neurosurg. 1997 Aug;99(3):213-6. doi: 10.1016/s0303-8467(97)00024-3.


A story told by his mother was presented on tape to a trauma patient in persistent vegetative state (PVS). During auditory presentation, measurements of regional cerebral blood flow (rCBF) were performed by means of positron emission tomography (PET). Changes in rCBF related to this stimulus condition, as compared to presenting non-word sound, were evaluated by means of statistical parametric mapping (SPM). This analysis indicated activation of rostral anterior cingulate, right middle temporal and right premotor cortices, which may reflect appropriate cortical involvement in processing emotional attributes of sound or speech.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Affect / physiology*
  • Cerebral Cortex / blood supply
  • Cerebral Cortex / physiopathology*
  • Cerebrovascular Circulation / physiology*
  • Humans
  • Male
  • Persistent Vegetative State* / physiopathology
  • Persistent Vegetative State* / psychology
  • Speech Perception / physiology*
  • Tomography, Emission-Computed*