Surgical strategy for doubly committed subarterial ventricular septal defect with aortic cusp prolapse

Ann Thorac Surg. 1997 Oct;64(4):1146-9. doi: 10.1016/s0003-4975(97)00718-2.


Background: Many surgeons recommend early repair of doubly committed subarterial ventricular septal defect regardless of the clinical symptoms. We reviewed our patients of this anomaly with aortic cusp prolapse to justify this strategy.

Methods: We reviewed the preoperative and postoperative records of 27 patients with doubly committed subarterial ventricular septal defect and aortic cusp prolapse. The patients' ages ranged from 2 months to 11 years (median, 4.6 years).

Results: During the preoperative observation period, aortic regurgitation (AR) developed in 65% of the patients. In the 8 patients without AR before the operation, AR did not develop after the operation, whereas AR persisted in 12 (63%) of the 19 patients with preoperative AR. To identify the risk factors for persistent AR after the operation we analyzed the data for the patients with preoperative AR in the persistent AR group (n = 12) and eliminated AR group (n = 7) and found a longer period from the onset of AR to the operation in the persistent AR group (32.1 +/- 10.1 versus 5.6 +/- 1.9 months; p = 0.014). During the follow-up period 10 of the 17 patients with mild AR before the operation showed persistent AR in the postoperative period, but it did not progress.

Conclusions: We conclude that early surgical repair with a minimum observation period is essential for prevention of residual AR. Even if a tiny AR is detected preoperatively, the patient should be surgically treated immediately.

MeSH terms

  • Age Factors
  • Aortic Valve Insufficiency / etiology*
  • Aortic Valve Prolapse / complications
  • Aortic Valve Prolapse / surgery*
  • Child
  • Child, Preschool
  • Follow-Up Studies
  • Heart Septal Defects, Ventricular / complications
  • Heart Septal Defects, Ventricular / surgery*
  • Humans
  • Infant
  • Retrospective Studies
  • Risk Factors