Tetracycline and niacinamide for the treatment of sterile pyogranuloma/granuloma syndrome in a dog

J Am Anim Hosp Assoc. Nov-Dec 1997;33(6):540-3. doi: 10.5326/15473317-33-6-540.

Abstract

A sterile pyogranuloma/granuloma syndrome in a dog is described. Diagnosis was based on cytological examinations of the skin and lymph nodes and histopathological examinations of the skin and nictitans. Although the condition initially was responsive to large doses of glucocorticoids, it subsequently was treated successfully with tetracycline and niacinamide. The excellent responses of this dog suggest that this drug combination may be a viable therapeutic option for dogs in which glucocorticoids cannot be used.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use*
  • Biopsy / methods
  • Biopsy / veterinary
  • Dog Diseases / drug therapy*
  • Dog Diseases / pathology
  • Dogs
  • Drug Therapy, Combination
  • Granuloma / drug therapy
  • Granuloma / pathology
  • Granuloma / veterinary*
  • Lymph Nodes / pathology
  • Male
  • Niacinamide / therapeutic use*
  • Skin / pathology
  • Skin Diseases / drug therapy
  • Skin Diseases / pathology
  • Skin Diseases / veterinary*
  • Syndrome
  • Tetracycline / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Niacinamide
  • Tetracycline