Abstract
From Dragon's Blood, a resin produced by plants of the genus Daemonorops (Palmae), six new A-type flavanoid deoxyproanthocyanidins have been isolated. Their structure and stereochemistry, established by chemical degradation and extensive NMR analysis, is consistent with a mechanism of formation common to other constituents of the resin, which involves oxidation of a 6-methylflavan to a quinonemethide, followed by coupling with another flavan moiety.
MeSH terms
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / chemistry
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Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Flavonoids / toxicity
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Mice
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Plants, Medicinal / chemistry*
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Rats
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Flavonoids