Progressive left main coronary artery obstruction leading to myocardial infarction in a child with Williams syndrome

Eur J Pediatr. 1997 Oct;156(10):751-3. doi: 10.1007/s004310050705.


We report a 3-year-old child with Williams syndrome in whom the first vascular feature of the syndrome was a myocardial infarction related to the occlusion of the left main coronary artery trunk. This coronary artery occlusion was not associated with supravalvular aortic stenosis.

Conclusion: This report emphazises that acute vascular events related to systemic artery anomalies may reveal Williams syndrome.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Chromosomes, Human, Pair 7
  • Coronary Angiography
  • Coronary Artery Bypass*
  • Elastin / genetics
  • Humans
  • Long QT Syndrome / diagnostic imaging
  • Long QT Syndrome / genetics
  • Long QT Syndrome / surgery
  • Male
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / genetics
  • Myocardial Infarction / surgery*
  • Risk Factors
  • Williams Syndrome / diagnostic imaging
  • Williams Syndrome / genetics
  • Williams Syndrome / surgery*


  • Elastin