Vero cytotoxin-producing Escherichia coli O157 outbreaks in England and Wales, 1995: phenotypic methods and genotypic subtyping

Emerg Infect Dis. 1997 Oct-Dec;3(4):561-5. doi: 10.3201/eid0304.970422.


Vero cytotoxin-producing Escherichia coli O157 belonging to four phage types (PTs) caused 11 outbreaks of infection in England and Wales in 1995. Outbreak strains of different PTs were distinguishable by DNA-based methods. Pulsed-field gel electrophoresis best discriminated among strains belonging to the same PT, distinguishing six of the seven PT2 outbreak strains and both PT49 outbreak strains.

Publication types

  • Review

MeSH terms

  • Bacterial Toxins / biosynthesis
  • Bacterial Toxins / genetics*
  • Disease Outbreaks*
  • Electrophoresis, Gel, Pulsed-Field
  • England / epidemiology
  • Escherichia coli Infections / epidemiology*
  • Escherichia coli Infections / microbiology
  • Escherichia coli O157 / classification*
  • Genotype
  • Humans
  • Phenotype
  • Shiga Toxin 1
  • Time Factors
  • Wales / epidemiology


  • Bacterial Toxins
  • Shiga Toxin 1