Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery

J Oral Maxillofac Surg. 1997 Nov;55(11):1294-9. doi: 10.1016/s0278-2391(97)90187-7.


The preparation and use of platelet gel, an autologous formulation of fibrin glue, are described. The unique features of this biologic sealant are that it is derived from autologous blood collected in the immediate preoperative period by the anesthesiologist, it contains a high concentration of platelets, and it can be used in patients who are not candidates for blood bank donation. Platelet gel has been used successfully in the area of reconstructive oral and maxillofacial surgery in conjunction with ablative surgery of the maxillofacial region, mandibular reconstruction, surgical repair of alveolar clefts and associated oral-antral/ oral-nasal fistulas, and adjunctive procedures related to the placement of osseointegrated implants.

MeSH terms

  • Blood
  • Blood Platelets*
  • Calcium Chloride / chemistry
  • Cell Degranulation
  • Cleft Palate / surgery
  • Dental Implantation, Endosseous
  • Face / surgery*
  • Fibrin Tissue Adhesive / chemical synthesis
  • Fibrin Tissue Adhesive / therapeutic use*
  • Fistula / surgery
  • Gels
  • Hemostatics / chemical synthesis
  • Hemostatics / therapeutic use*
  • Humans
  • Mandible / surgery
  • Mouth / surgery*
  • Nose Diseases / surgery
  • Oral Fistula / surgery
  • Oroantral Fistula / surgery
  • Orthognathic Surgical Procedures*
  • Osseointegration
  • Plastic Surgery Procedures
  • Preoperative Care
  • Thrombin / chemistry
  • Tissue Adhesives / chemical synthesis
  • Tissue Adhesives / therapeutic use*
  • Transplantation, Autologous


  • Fibrin Tissue Adhesive
  • Gels
  • Hemostatics
  • Tissue Adhesives
  • Thrombin
  • Calcium Chloride