Development of the Kidney Vasculature

Microsc Res Tech. 1997 Nov 1;39(3):254-60. doi: 10.1002/(SICI)1097-0029(19971101)39:3<254::AID-JEMT5>3.0.CO;2-K.

Abstract

Renal vascularization and nephrogenesis occur simultaneously following a tightly regulated developmental program influenced by growth factors, extracellular matrix components and cell membrane receptors. Both processes of angiogenesis and vasculogenesis probably participate in the formation of renal vessels. The origin and fate of the various renal vascular cells and the molecular mechanisms that initiate and guide intrarenal vascularization are fundamental questions that remain to be answered.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Blood Vessels / embryology
  • Humans
  • Kidney / blood supply*
  • Kidney / embryology*
  • Morphogenesis
  • Neovascularization, Physiologic