Adverse side effects associated with latanoprost

Am J Ophthalmol. 1997 Nov;124(5):683-5. doi: 10.1016/s0002-9394(14)70907-9.


Purpose: To report three different adverse reactions after initiating treatment with latanoprost.

Method: Serial clinical examinations of three patients were performed.

Results: Adverse reactions such as ocular hypotony and choroidal effusions, recurrent cystoid macular edema, and facial rash were noted to occur within 1 to 4 weeks after starting topical latanoprost for the treatment of primary open-angle glaucoma.

Conclusion: Clinicians should be alerted to these possible complications of topical latanoprost therapy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroid Diseases / chemically induced*
  • Exanthema / chemically induced*
  • Female
  • Fluorescein Angiography
  • Glaucoma, Open-Angle / drug therapy
  • Humans
  • Intraocular Pressure
  • Latanoprost
  • Macular Edema / chemically induced*
  • Male
  • Ocular Hypotension / chemically induced*
  • Ophthalmic Solutions
  • Prostaglandins F, Synthetic / administration & dosage
  • Prostaglandins F, Synthetic / adverse effects*
  • Recurrence


  • Ophthalmic Solutions
  • Prostaglandins F, Synthetic
  • Latanoprost