Efficacy of proton therapy in circumscribed choroidal hemangiomas associated with serious retinal detachment

Ophthalmology. 1997 Nov;104(11):1780-4. doi: 10.1016/s0161-6420(97)30026-8.


Objective: The purpose of the study is to evaluate the efficacy and safety of proton therapy in complicated circumscribed choroidal hemangiomas.

Design: The study design was a retrospective review.

Participants: Studied were 13 patients (13 eyes) who had circumscribed choroidal hemangioma associated with serous retinal detachment. Of these, four eyes previously underwent laser unsuccessfully.

Intervention: Proton therapy including a total dose of 30 Cobalt-Gray-Equivalent was administered to each eye.

Main outcome measures: Patients were controlled for initial and final best-corrected visual acuity, slit-lamp examination, intraocular pressure, fundus examination, fluorescein angiography, and tumor thickness on B-scan ultrasonography.

Results: The mean follow-up period was 26 months (range, 9-48 months). Retinal reattachment was obtained in all cases after a mean period of 52 days. The tumor height decreased in all cases. Visual acuity improved to two lines or more in eight eyes (62%) and reached 20/200 or more in nine eyes (69%). No radiation complication was detected during follow-up.

Conclusions: Proton radiation seems to be effective and safe in the management of choroidal hemangioma associated with serous retinal detachment. It may be useful when photocoagulation can not be performed.

MeSH terms

  • Adult
  • Aged
  • Choroid Neoplasms / complications
  • Choroid Neoplasms / physiopathology
  • Choroid Neoplasms / radiotherapy*
  • Exudates and Transudates
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Hemangioma / complications
  • Hemangioma / physiopathology
  • Hemangioma / radiotherapy*
  • Humans
  • Male
  • Middle Aged
  • Protons
  • Radiotherapy, High-Energy*
  • Retinal Detachment / complications*
  • Retinal Detachment / physiopathology
  • Retrospective Studies
  • Visual Acuity


  • Protons