Corneal endothelial damage associated with phacoemulsification

Am J Ophthalmol. 1976 Jul;82(1):48-54. doi: 10.1016/0002-9394(76)90663-2.


Twenty-one cats underwent standard Kelman phacoemulsification procedures in their right eyes. The left eyes of the same amimals underwent a planned extracapsular cataract extraction or irrigation and aspiration for 15 minutes using the Kelman phacoemulsification unit. The corneal endothelium was evaluated at various times postoperatively using a stain for endothelial cell viability and scanning electron microscopy. The results suggested that the irrigation procedure alone is deleterious to the cat endothelium as is the rubbing of nuclear material against the endothelial cells. These two procedures caused additonal damage when combined in a routine phacoemulsification procedure.

MeSH terms

  • Animals
  • Cataract Extraction / adverse effects*
  • Cats
  • Cornea / ultrastructure
  • Corneal Diseases / etiology*
  • Endothelium / ultrastructure
  • Therapeutic Irrigation / adverse effects*
  • Ultrasonic Therapy / adverse effects*