Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 273 (5), R1569-71

The Imidazoline Receptor in Control of Blood Pressure by Clonidine and Allied Drugs

Affiliations
Review

The Imidazoline Receptor in Control of Blood Pressure by Clonidine and Allied Drugs

D J Reis et al. Am J Physiol.

Abstract

Clonidine, moxonidine, and rilmenidine are centrally acting antihypertensive agents that lower arterial pressure by inhibiting the tonic activity of sympathoexcitatory neurons in the rostral ventrolateral medulla. Competing hypotheses have been put forward by different investigators to explain the sympathoinhibition evoked by "imidazoline drugs": either via central actions at alpha 2-adrenergic receptors or novel I1-imidazoline receptors. These different perspectives are presented in the accompanying reviews.

Similar articles

See all similar articles

Cited by 6 PubMed Central articles

See all "Cited by" articles

LinkOut - more resources

Feedback