From adaptation to maladaptation--an introduction to the spectrum of circulatory responses in health and disease

Ann Med. 1997 Aug;29(4):311-2. doi: 10.3109/07853899708999353.

Abstract

The cardiovascular system can be described as a network of constantly oscillating physical, hormonal and neural feedback loops. They operate in a concerted fashion in order to provide the body with its daily needs. Inability to maintain cardiovascular homeostasis may be the result of relatively well-tolerated but repeated disturbances, or a single overwhelming event. The development of clinical cardiovascular disease may thus be viewed as failure to compensate for such alterations successfully.

MeSH terms

  • Adaptation, Physiological*
  • Blood Circulation / physiology*
  • Cardiovascular Diseases / physiopathology*
  • Homeostasis*
  • Humans