NMR structures of proteins and protein complexes beyond 20,000 M(r)

Nat Struct Biol. 1997 Oct;4 Suppl:849-53.

Abstract

Recent advances in multidimensional NMR to obtain resonance assignments, interproton distance and torsion angle restraints, and restraints that characterize long range order, coupled with new methods of structure refinement, have permitted solution structures of proteins in excess of 250 residues to be solved.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Macromolecular Substances
  • Mathematics
  • Models, Structural*
  • Molecular Weight
  • Nuclear Magnetic Resonance, Biomolecular / methods*
  • Protein Structure, Secondary
  • Proteins / chemistry*

Substances

  • Macromolecular Substances
  • Proteins