Experience of mini-invasive interventions in 180 patients with hepatic cirrhosis (HC), complicated by portal hypertension syndrome in decompensation stage was summarized. High risk of laparotomy in this patients made its conduction impossible. Mini-invasive interventions included the truncus coeliacus branches embolization, peritoneovenous shunting, endoscopic sclerotherapy of esophageal varicose veins. Total mortality constituted 6%. There were few severe complications. Most frequent rate (81% of observations) of fair results in the late period was noted after conduction of consecutive interventions. It promoted the increase of patients life span. The staged tactic of treatment constitutes a new perspective trend in the treatment of patients with complicated HC.