Abstract
Urinary tract infections (UTI) are caused by a variety of gram-negative bacteria that ascend into the urinary tract and establish bacteriuria often at levels greater than or equal to 10(5) bacteria/ mL of urine. Escherichia coli dominate as the causative agent in all patient groups, with Staphylococcus saprophyticus as the second most common, accounting for about 10% to 30% of the infections in young adult women depending on the season. This article covers the pathogenesis and inflammatory response of UTI and the virulence factors of uropathogenic E. coli.
MeSH terms
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Adult
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Clone Cells
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Escherichia coli / genetics
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Escherichia coli / metabolism
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Escherichia coli / pathogenicity*
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Escherichia coli Infections / immunology
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Escherichia coli Infections / metabolism
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Escherichia coli Infections / microbiology*
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Female
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Hemolysin Proteins / metabolism
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Humans
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Hydroxamic Acids / metabolism
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Inflammation / microbiology
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Lipopolysaccharides / metabolism
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Polysaccharides, Bacterial / metabolism
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Urinary Tract Infections / immunology
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Urinary Tract Infections / metabolism
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Urinary Tract Infections / microbiology*
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Virulence
Substances
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Hemolysin Proteins
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Hydroxamic Acids
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Lipopolysaccharides
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Polysaccharides, Bacterial
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aerobactin