Dictyostelium development: lower STATs

Curr Biol. 1997 Nov 1;7(11):R723-5. doi: 10.1016/s0960-9822(06)00366-6.

Abstract

The discovery of a STAT protein in Dictyostelium indicates that this organism uses phosphotyrosine-SH2-domain signalling during development. Such signalling is lacking in yeast and its appearance may therefore be an early step in the evolution of multicellularity.

Publication types

  • Review

MeSH terms

  • Animals
  • DNA-Binding Proteins / physiology*
  • Dictyostelium / cytology
  • Dictyostelium / growth & development*
  • Dictyostelium / physiology
  • Signal Transduction / physiology*
  • Trans-Activators / physiology*

Substances

  • DNA-Binding Proteins
  • Trans-Activators