Intraoperative functional MRI using a real-time neurosurgical navigation system

J Comput Assist Tomogr. 1997 Nov-Dec;21(6):910-2. doi: 10.1097/00004728-199711000-00013.


A 42-year-old-man had focal left hand motor seizures. MR studies demonstrated a right posterior frontal brain tumor. Functional MRI was performed, localizing the motor cortex posterior to the lesion. The functional images were integrated with a neurosurgical navigation computer. A real-time intraoperative display of the anatomic and functional images was produced, registered to a neurosurgical probe. Excellent correlation was demonstrated between the functional maps and invasive electrophysiologic mapping performed at the time of craniotomy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / surgery*
  • Humans
  • Image Processing, Computer-Assisted
  • Intraoperative Period
  • Magnetic Resonance Imaging / methods*
  • Male
  • Motor Cortex / pathology*