High iron status in very low birth weight infants is associated with an increased risk of retinopathy of prematurity

J Pediatr. 1997 Oct;131(4):541-4. doi: 10.1016/s0022-3476(97)70058-1.


To explore the hypothesis that excessive iron loads may increase the formation of free radicals and the development of retinopathy of prematurity in preterm infants, we carried out a prospective observational study of the association between transfusion volume, iron status, and retinopathy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ferritins / blood*
  • Humans
  • Infant, Newborn
  • Infant, Very Low Birth Weight*
  • Oxygen Inhalation Therapy
  • Prospective Studies
  • Retinopathy of Prematurity / blood
  • Retinopathy of Prematurity / diagnosis*
  • Retinopathy of Prematurity / epidemiology
  • Retinopathy of Prematurity / therapy
  • Retrospective Studies
  • Risk Factors
  • Statistics, Nonparametric
  • Time Factors


  • Ferritins