TRANSFAC database as a bridge between sequence data libraries and biological function

Pac Symp Biocomput. 1997;477-85.

Abstract

The TRANSFAC database contains information about regulatory DNA sequences and the proteins (transcription factors) binding to and acting through them. It may thus serve as a dictionary for the biological meaning of these sequence elements. Moreover, the TRANSFAC data can be used to describe these elements, to define consensi and matrices for elements of certain function, and thus to provide means of identifying regulatory signals in newly unravelled genomic sequences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Binding Sites
  • Computer Communication Networks
  • Consensus Sequence
  • DNA / chemistry*
  • DNA / genetics*
  • DNA / metabolism
  • Databases as Topic*
  • Genes
  • Information Storage and Retrieval
  • Regulatory Sequences, Nucleic Acid
  • Sequence Alignment
  • Transcription Factors / metabolism*

Substances

  • Transcription Factors
  • DNA