Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1997 Dec;83(6):2055-63.
doi: 10.1152/jappl.1997.83.6.2055.

Long-term Creatine Intake Is Beneficial to Muscle Performance During Resistance Training

Affiliations
Free article
Clinical Trial

Long-term Creatine Intake Is Beneficial to Muscle Performance During Resistance Training

K Vandenberghe et al. J Appl Physiol (1985). .
Free article

Abstract

The effects of oral creatine supplementation on muscle phosphocreatine (PCr) concentration, muscle strength, and body composition were investigated in young female volunteers (n = 19) during 10 wk of resistance training (3 h/wk). Compared with placebo, 4 days of high-dose creatine intake (20 g/day) increased (P < 0.05) muscle PCr concentration by 6%. Thereafter, this increase was maintained during 10 wk of training associated with low-dose creatine intake (5 g/day). Compared with placebo, maximal strength of the muscle groups trained, maximal intermittent exercise capacity of the arm flexors, and fat-free mass were increased 20-25, 10-25, and 60% more (P < 0. 05), respectively, during creatine supplementation. Muscle PCr and strength, intermittent exercise capacity, and fat-free mass subsequently remained at a higher level in the creatine group than in the placebo group during 10 wk of detraining while low-dose creatine was continued. Finally, on cessation of creatine intake, muscle PCr in the creatine group returned to normal within 4 wk. It is concluded that long-term creatine supplementation enhances the progress of muscle strength during resistance training in sedentary females.

Similar articles

See all similar articles

Cited by 72 articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback