Growth hormone treatment of short children born small for gestational age

Acta Paediatr Suppl. 1997 Nov;423:213-5. doi: 10.1111/j.1651-2227.1997.tb18419.x.

Abstract

The administration of growth hormone (GH) for a short period to short children born small for gestational age increases growth velocity. Children receiving 2-3 times the replacement dose gained nearly 2.0 SDS in height over a 3-year treatment period. This treatment is well tolerated, without significant side-effects. Further studies of the growth rate following cessation of GH treatment will reveal whether the gain in height is maintained, and whether the final height prediction is improved.

Publication types

  • Review

MeSH terms

  • Body Height / drug effects*
  • Child, Preschool
  • Fetal Growth Retardation / etiology
  • Human Growth Hormone / therapeutic use*
  • Humans
  • Infant, Small for Gestational Age / growth & development*

Substances

  • Human Growth Hormone