Filamentous growth in budding yeast

Trends Microbiol. 1997 Nov;5(11):450-4. doi: 10.1016/S0966-842X(97)01131-1.


The recent discovery that some laboratory strains of Saccharomyces cerevisiae are capable of limited filamentous growth has stimulated genetic analysis of dimorphism in this microorganism. The puzzle of why most strains are nonfilamentous is now resolved. Remarkably, a single point mutation with broad consequences separates these domesticated yeast from their wild ancestors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Candida albicans / genetics
  • Candida albicans / growth & development
  • Diploidy
  • Flocculation
  • Genes, Fungal
  • Haploidy
  • Point Mutation
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / growth & development*