Computer-assisted adjustment of inspired oxygen concentration improves control of oxygen saturation in newborn infants requiring mechanical ventilation

J Pediatr. 1997 Nov;131(5):754-6. doi: 10.1016/s0022-3476(97)70107-0.


Open-loop computer control of inspired oxygen concentration was evaluated in 16 newborn infants requiring mechanical ventilation. FIO2 and oxygen saturation were compared for 2-hour periods of computer versus routine manual FIO2 adjustment. During computer-assisted FIO2 adjustment, patients spent more time at the target SaO2 and less time with SaO2 < 90%.

Publication types

  • Clinical Trial

MeSH terms

  • Humans
  • Infant, Newborn
  • Oximetry
  • Oxygen Consumption*
  • Respiration, Artificial*
  • Therapy, Computer-Assisted*