Lymphocyte homeostasis

Semin Immunol. 1997 Dec;9(6):331-7. doi: 10.1006/smim.1997.0090.


B- and T-lymphocyte populations have an independent homeostatic regulation of resting (B and T) and activated (B) or memory (T) cell compartments. This organization may provide an efficient mechanism to ensure simultaneously a first natural barrier of protection against common pathogens, the maintenance of immunological T-cell memory and a reservoir of repertoire diversity capable of dealing with new antigenic challenges.

Publication types

  • Review

MeSH terms

  • Animals
  • B-Lymphocytes / immunology*
  • Bone Marrow Cells
  • Homeostasis*
  • Immunologic Memory
  • Lymphocyte Activation
  • Mice
  • Models, Immunological*
  • T-Lymphocytes / immunology*
  • Thymus Gland