Lymphangioleiomyomatosis: recurrence after single lung transplantation

Hum Pathol. 1997 Dec;28(12):1420-3. doi: 10.1016/s0046-8177(97)90233-1.


Lymphangioleiomyomatosis (LAM) is a rare disease which afflicts young women of childbearing age. Recently, it has been listed as an indication for lung transplantation. We describe a case of recurrent LAM in a 31-year-old woman occurring in the allograft of a male donor after single lung transplantation. Nonisotopic in situ hybridization shows that the smooth muscle cell proliferation is of donor origin.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cell Division
  • Female
  • Humans
  • Lung Transplantation / pathology*
  • Lymphangioleiomyomatosis / pathology*
  • Lymphangioleiomyomatosis / surgery*
  • Muscle, Smooth / pathology
  • Postoperative Complications / pathology*
  • Pulmonary Alveoli / pathology
  • Recurrence