Hospitalizations associated with rotavirus diarrhea in the United States, 1993 through 1995: surveillance based on the new ICD-9-CM rotavirus-specific diagnostic code

J Infect Dis. 1998 Jan;177(1):13-7. doi: 10.1086/513808.


The introduction of a specific International Classification of Diseases code for rotavirus diarrhea in 1992 prompted examination of the National Hospital Discharge Survey (NHDS) for trends in rotavirus-associated hospitalizations among US children aged 1 month through 4 years. During 1993-1995, 13.5% of hospitalizations were associated with diarrhea (n = 162,478/year). Rotavirus was the most common pathogen identified, coded in 16.5% of diarrhea cases (n = 26,798/year), and increased from 13.3% in 1993 to 18.9% in 1995. The age distribution and seasonality of hospitalizations of presumed noninfectious and viral etiology resembled those associated with rotavirus. Rotavirus was reported as a cause of diarrhea more frequently by hospitals that were large (> or =100 beds), proprietary-owned, or in the West/Midwest. Although these findings suggest incomplete detection of rotavirus diarrhea cases, the large number of rotavirus-associated hospitalizations underscores the need for vaccines and indicates that NHDS data could be used to monitor the impact of a US rotavirus immunization program.

MeSH terms

  • Age Factors
  • Child, Preschool
  • Diarrhea / diagnosis
  • Diarrhea / epidemiology
  • Diarrhea / etiology
  • Hospitalization / trends*
  • Hospitals, Private
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Population Surveillance
  • Rotavirus Infections / classification
  • Rotavirus Infections / diagnosis
  • Rotavirus Infections / epidemiology*
  • Seasons
  • Sex Factors
  • United States / epidemiology