A case of nondigitalis cardiac glycoside toxicity

Ther Drug Monit. 1997 Dec;19(6):711-4. doi: 10.1097/00007691-199712000-00018.

Abstract

A case is presented of cardiac glycoside poisoning in a 1-year-old patient from the plant Nerium oleander (common oleander). The patient had bradycardia, vomiting, altered level of consciousness, and no history of ingestion. Antibody-based digoxin assays may cross-react with other cardiac glycosides nonquantitatively. Chromatographic techniques can be used in the specific diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anti-Arrhythmia Agents / immunology
  • Bradycardia / etiology*
  • Cardenolides / isolation & purification
  • Chromatography, High Pressure Liquid
  • Cross Reactions
  • Digoxin / immunology
  • False Positive Reactions
  • Glycosides / poisoning*
  • Humans
  • Immunoassay / methods
  • Infant
  • Male
  • Plant Poisoning / complications*
  • Vomiting / etiology

Substances

  • Anti-Arrhythmia Agents
  • Cardenolides
  • Glycosides
  • oleandrigenin
  • Digoxin
  • oleandrin