Induction of drug-metabolizing enzymes by dioxin

Drug Metab Rev. 1997 Nov;29(4):1107-27. doi: 10.3109/03602539709002245.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Aryl Hydrocarbon Hydroxylases*
  • Aryl Hydrocarbon Receptor Nuclear Translocator
  • Basic Helix-Loop-Helix Transcription Factors
  • Chromatin
  • Cytochrome P-450 CYP1A1 / biosynthesis
  • Cytochrome P-450 CYP1A1 / drug effects*
  • Cytochrome P-450 CYP1A1 / genetics
  • Cytochrome P-450 CYP1A2 / biosynthesis
  • Cytochrome P-450 CYP1A2 / drug effects
  • Cytochrome P-450 CYP1A2 / genetics
  • Cytochrome P-450 CYP1B1
  • Cytochrome P-450 Enzyme System / biosynthesis
  • Cytochrome P-450 Enzyme System / drug effects
  • Cytochrome P-450 Enzyme System / genetics
  • DNA-Binding Proteins / metabolism
  • Dioxins / pharmacology*
  • Enhancer Elements, Genetic / genetics
  • Enzyme Induction
  • Female
  • Gene Expression Regulation, Enzymologic
  • Glutathione Transferase / biosynthesis
  • Glutathione Transferase / drug effects
  • Male
  • NADH, NADPH Oxidoreductases / biosynthesis
  • NADH, NADPH Oxidoreductases / drug effects
  • Pharmaceutical Preparations / metabolism
  • Polychlorinated Dibenzodioxins / pharmacology*
  • Promoter Regions, Genetic / genetics
  • Rats
  • Receptors, Aryl Hydrocarbon*
  • Transcription Factors / metabolism
  • Transcriptional Activation

Substances

  • ARNT protein, rat
  • Basic Helix-Loop-Helix Transcription Factors
  • Chromatin
  • DNA-Binding Proteins
  • Dioxins
  • Pharmaceutical Preparations
  • Polychlorinated Dibenzodioxins
  • Receptors, Aryl Hydrocarbon
  • Transcription Factors
  • Aryl Hydrocarbon Receptor Nuclear Translocator
  • Cytochrome P-450 Enzyme System
  • Aryl Hydrocarbon Hydroxylases
  • Cyp1b1 protein, rat
  • Cytochrome P-450 CYP1A1
  • Cytochrome P-450 CYP1A2
  • Cytochrome P-450 CYP1B1
  • NADH, NADPH Oxidoreductases
  • Glutathione Transferase