A succinylanthranilic acid ester and other bioactive constituents of Jolyna laminarioides

Phytochemistry. 1997 Dec;46(7):1215-8.

Abstract

Methyl 2-[propanamide-2'-methoxycarbonyl] benzoate, fucosterol, trans-phytol and p-formylphenol were isolated for the first time from a methanolic extract of Jolyna laminarioides. Methyl 2-[propanamide-2'-methoxycarbonyl]-benzoate exhibited chymotrypsin inhibitory activity and also found to be active against Escherichia coli and Shigella boydii. Fucosterol exhibited antifungal activity against Curvularia lunata, Stachybotrys atra and Microsporum canis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemistry*
  • Anti-Infective Agents / isolation & purification
  • Anti-Infective Agents / pharmacology
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology
  • Bacteria / drug effects*
  • Benzaldehydes / chemistry*
  • Benzaldehydes / isolation & purification
  • Benzaldehydes / pharmacology
  • Benzoates / chemistry*
  • Benzoates / isolation & purification
  • Benzoates / pharmacology
  • Chymotrypsin / antagonists & inhibitors
  • Escherichia coli / drug effects
  • Fungi / drug effects*
  • Microbial Sensitivity Tests
  • Microsporum / drug effects
  • Molecular Structure
  • Phaeophyceae / chemistry*
  • Phytol / chemistry*
  • Phytol / isolation & purification
  • Phytol / pharmacology
  • Plant Extracts
  • Protease Inhibitors / chemistry
  • Protease Inhibitors / isolation & purification
  • Protease Inhibitors / pharmacology
  • Shigella boydii / drug effects
  • Stigmasterol / analogs & derivatives*
  • Stigmasterol / chemistry
  • Stigmasterol / isolation & purification
  • Stigmasterol / pharmacology

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Benzaldehydes
  • Benzoates
  • Plant Extracts
  • Protease Inhibitors
  • methyl-2-(propanamide-2'-methoxycarbonyl)benzoate
  • Phytol
  • fucosterol
  • Stigmasterol
  • Chymotrypsin
  • 4-hydroxybenzaldehyde