Post-translational modification of proteins and the discovery of new medicine

Curr Opin Biotechnol. 1997 Dec;8(6):718-23. doi: 10.1016/s0958-1669(97)80126-7.


Post-translational modifications are fundamental to processes controlling behaviour, including cellular signaling, growth and transformation. As the molecular basis of protein modifications in normal and disease processes are becoming better defined, so new strategies for designing therapeutic entities to control complex disease processes are emerging.

Publication types

  • Review

MeSH terms

  • Drug Design*
  • Humans
  • Protein Processing, Post-Translational*
  • Proteins / metabolism*


  • Proteins