Organization of DNA sequences near the centromere of the Drosophila melanogaster Y chromosome

Chromosoma. 1997 Dec;106(8):503-12. doi: 10.1007/s004120050272.


The structural analysis of a yeast artificial chromosome clone from Drosophila melanogaster enriched in dodecasatellite sequences has led us to find a new retrotransposon that we have called Circe. Moreover, this retrotransposon has allowed the isolation of a contig encompassing approximately 200 kb near the centromere of the Y chromosome, providing an entry point into a region from which very little sequence information has been obtained to date. The molecular characterization of the contig has shown the presence of HeT-A telomeric retrotransposons close to the centromere of the Y chromosome, suggesting a telocentric origin for this submetacentric chromosome.

MeSH terms

  • Animals
  • Base Sequence
  • Centromere / chemistry
  • Centromere / genetics*
  • Chromosome Mapping
  • Chromosomes, Artificial, Yeast / chemistry
  • Chromosomes, Artificial, Yeast / genetics
  • DNA / analysis*
  • DNA / genetics*
  • DNA Transposable Elements*
  • Drosophila Proteins*
  • Drosophila melanogaster / genetics*
  • Gene Products, gag*
  • Insect Proteins / genetics
  • Molecular Sequence Data
  • Retroelements / genetics
  • Sequence Analysis, DNA*
  • Y Chromosome / chemistry
  • Y Chromosome / genetics*


  • DNA Transposable Elements
  • Drosophila Proteins
  • Gene Products, gag
  • HeT-A-gag protein, Drosophila
  • Insect Proteins
  • Retroelements
  • DNA

Associated data

  • GENBANK/X83487