Progressive supranuclear palsy and corticobasal degeneration

Baillieres Clin Neurol. 1997 Apr;6(1):167-85.


The clinical and neuropathological features characteristic of progressive supranuclear palsy and corticobasal degeneration are described in detail. These disorders are not as rare as previously believed, but are poorly recognized. In patients with parkinsonism, a high index of clinical suspicion, sometimes complemented by specific laboratory tests, should improve diagnostic accuracy. Biological treatments are at present not available, but suggested symptomatic therapies may improve the quality of life of patients with these disorders.

Publication types

  • Review

MeSH terms

  • Basal Ganglia / pathology
  • Brain Stem / pathology
  • Cerebral Cortex / pathology
  • Diagnosis, Differential
  • Diagnostic Imaging
  • Humans
  • Neuropsychological Tests
  • Parkinson Disease, Secondary / diagnosis*
  • Parkinson Disease, Secondary / physiopathology
  • Parkinson Disease, Secondary / therapy
  • Quality of Life
  • Supranuclear Palsy, Progressive / diagnosis*
  • Supranuclear Palsy, Progressive / physiopathology
  • Supranuclear Palsy, Progressive / therapy