Rainbow trout SOX9: cDNA cloning, gene structure and expression

Gene. 1997 Nov 20;202(1-2):167-70. doi: 10.1016/s0378-1119(97)00483-6.

Abstract

We have isolated and characterized rainbow trout SOX9 cDNA and genomic clones. The cDNA encodes a protein of 488 amino acids (aa) with an HMG box and has 70% aa sequence identity with human SOX9. The rainbow trout and human SOX9 genes show a similar gene structure, and the two introns in the coding region are located at conserved positions. In rainbow trout, the SOX9 mRNA was prominent in testis and brain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Northern
  • Chickens
  • Cloning, Molecular
  • DNA, Complementary / chemistry
  • DNA, Complementary / isolation & purification*
  • Gene Expression Regulation*
  • High Mobility Group Proteins / biosynthesis
  • High Mobility Group Proteins / genetics*
  • Humans
  • Male
  • Mice
  • Molecular Sequence Data
  • Oncorhynchus mykiss / genetics*
  • RNA, Messenger / analysis
  • SOX9 Transcription Factor
  • Sex Differentiation / genetics*
  • Testis
  • Transcription Factors / biosynthesis
  • Transcription Factors / genetics*

Substances

  • DNA, Complementary
  • High Mobility Group Proteins
  • RNA, Messenger
  • SOX9 Transcription Factor
  • SOX9 protein, human
  • Sox9 protein, mouse
  • Transcription Factors

Associated data

  • GENBANK/AB006448