Abstract
We have isolated and characterized rainbow trout SOX9 cDNA and genomic clones. The cDNA encodes a protein of 488 amino acids (aa) with an HMG box and has 70% aa sequence identity with human SOX9. The rainbow trout and human SOX9 genes show a similar gene structure, and the two introns in the coding region are located at conserved positions. In rainbow trout, the SOX9 mRNA was prominent in testis and brain.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Blotting, Northern
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Chickens
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Cloning, Molecular
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DNA, Complementary / chemistry
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DNA, Complementary / isolation & purification*
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Gene Expression Regulation*
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High Mobility Group Proteins / biosynthesis
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High Mobility Group Proteins / genetics*
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Humans
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Male
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Mice
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Molecular Sequence Data
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Oncorhynchus mykiss / genetics*
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RNA, Messenger / analysis
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SOX9 Transcription Factor
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Sex Differentiation / genetics*
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Testis
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Transcription Factors / biosynthesis
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Transcription Factors / genetics*
Substances
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DNA, Complementary
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High Mobility Group Proteins
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RNA, Messenger
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SOX9 Transcription Factor
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SOX9 protein, human
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Sox9 protein, mouse
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Transcription Factors