HIV vaccine acceptance among heterosexual clients of a sexually transmitted diseases clinic

Am J Med Sci. 1998 Jan;315(1):11-6. doi: 10.1097/00000441-199801000-00003.


We evaluated the willingness of clients at a large urban sexually transmitted diseases (STD) clinic in the southeastern United States to participate in future trials of preventive vaccines for HIV type 1 (HIV-1). A single trained interviewer administered an oral survey instrument to STD clinic clients over a 4-week enrollment period. The participants were 167 randomly selected clients (90 men and 77 women), most of whom were young, African-American heterosexuals. Risk behaviors for HIV-1 infection were highly prevalent. Overall, 67% of clients expressed willingness to consider participation in an HIV-1 vaccine trial. By univariate analysis, prior HIV-1 testing was significantly associated with willingness to participate (P = 0.04). Multivariate analysis revealed that female gender (P = 0.05) and prior HIV-1 testing (P = 0.03) were significant predictors of willingness to participate.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS Vaccines*
  • Acquired Immunodeficiency Syndrome / prevention & control*
  • Adult
  • Alabama
  • Analysis of Variance
  • Black or African American
  • Clinical Trials as Topic
  • Community Health Services
  • Female
  • HIV-1*
  • Heterosexuality
  • Humans
  • Male
  • Multivariate Analysis
  • Patient Acceptance of Health Care*
  • Risk-Taking
  • Sexually Transmitted Diseases
  • Southeastern United States
  • Surveys and Questionnaires
  • Urban Population
  • White People


  • AIDS Vaccines