Pro-inflammatory signaling: last pieces in the NF-kappaB puzzle?

Curr Biol. 1998 Jan 1;8(1):R19-22. doi: 10.1016/s0960-9822(98)70010-7.


The discovery of three previously unknown kinases that are essential for signaling in response to tumour necrosis factor and interleukin-1 has provided the missing link in the pathway that activates inflammatory genes.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Inflammation / etiology*
  • NF-kappa B / physiology*
  • Signal Transduction / physiology*


  • NF-kappa B