Secretion: dense-core vesicles can kiss-and-run too

Curr Biol. 1998 Jan 15;8(2):R62-5. doi: 10.1016/s0960-9822(98)70036-3.


New measurements show that the entire transmitter contents of a dense-core vesicle can be released within a second through a narrow fusion pore that opens transiently. With other results, this raises the possibility that some dense core vesicles may, like small synaptic vesicles, undergo immediate recycling.

Publication types

  • Review

MeSH terms

  • Catecholamines / metabolism
  • Cell Degranulation
  • Exocytosis / physiology*
  • Models, Biological
  • Neurotransmitter Agents / metabolism*
  • Organelles / metabolism*


  • Catecholamines
  • Neurotransmitter Agents