Pheochromocytoma and primary aldosteronism: diagnostic approaches

Endocrinol Metab Clin North Am. 1997 Dec;26(4):801-27. doi: 10.1016/s0889-8529(05)70283-8.


Although adrenal-dependent hypertension is an uncommon form of hypertension, its diagnosis provides clinicians with a unique treatment opportunity, that is, to render a surgical cure or to achieve a dramatic response to pharmacologic therapy. The diagnosis of catecholamine-secreting tumors has evolved during the last 70 years to a straightforward stepwise algorithmic approach. Primary aldosteronism is now recognized as the most common form of secondary hypertension, and the screening methods for it are simple and reliable.

Publication types

  • Review

MeSH terms

  • Adrenal Gland Neoplasms / diagnosis*
  • Adrenal Gland Neoplasms / diagnostic imaging
  • Adrenal Gland Neoplasms / therapy
  • Aged
  • Catecholamines / metabolism*
  • Catecholamines / urine
  • Female
  • Humans
  • Hyperaldosteronism / classification
  • Hyperaldosteronism / diagnosis*
  • Hyperaldosteronism / therapy
  • Male
  • Middle Aged
  • Pheochromocytoma / diagnosis*
  • Pheochromocytoma / diagnostic imaging
  • Pheochromocytoma / therapy
  • Radionuclide Imaging


  • Catecholamines