A double blind, randomized, controlled investigation of electrodermal testing in the diagnosis of allergies

J Altern Complement Med. Fall 1997;3(3):241-8. doi: 10.1089/acm.1997.3.241.


This investigation evaluates electrodermal (ED) testing in 41 polysymptomatic allergic patients. Electrodermal testing discriminated correctly 82% of the time between house dust mite and histamine (allergens) and saline or water (nonallergens) in our first study group involving 17 patients (p = 0.007). The second study involved 24 patients and used the same double-blind methodology discriminating 96% of the time between allergic and nonallergic substances (p = 0.000002). We conclude that ED testing is a reliable method of differentiating between allergic and nonallergic substances in the context of our study.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Acupuncture Points*
  • Adolescent
  • Adult
  • Aged
  • Animals
  • Child
  • Double-Blind Method
  • Female
  • Galvanic Skin Response*
  • Histamine / immunology
  • Humans
  • Hypersensitivity / diagnosis*
  • Male
  • Middle Aged
  • Mites / immunology
  • Reproducibility of Results


  • Histamine