Inadequate calcium, folic acid, vitamin E, zinc, and selenium intake in rheumatoid arthritis patients: results of a dietary survey

Semin Arthritis Rheum. 1997 Dec;27(3):180-5. doi: 10.1016/s0049-0172(97)80018-2.

Abstract

Objectives: To determine the adequacy of calcium, folic acid, vitamin E, zinc, and selenium intake in patients with rheumatoid arthritis (RA).

Methods: We conducted an observational study on 48 patients (13 men, 35 women; mean age, 64.5 years) with RA attending a specialty clinic in New Zealand comparing their dietary intake as measured by a 5-day dietary survey with recommended dietary intake (RDI) guidelines. Information on disease activity, functional ability, and drug therapy also was obtained.

Results: The percentage of patients who achieved the RDI was 23% for calcium, 46% for folic acid, 29% for vitamin E, 10% for zinc, and only 6% for selenium. Patients on methotrexate had a significantly reduced intake of folic acid as a percentage of RDI (P < .05) compared with those on other therapies. In contrast, dietary intake of iron and protein was largely adequate and unrelated to anemia.

Conclusions: Patients with RA should receive dietary education or supplementation to bring their intake of calcium, folic acid, vitamin E, zinc, and selenium up to the RDI.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arthritis, Rheumatoid / complications*
  • Calcium / deficiency*
  • Diet Surveys*
  • Female
  • Folic Acid Deficiency / complications*
  • Humans
  • Male
  • Middle Aged
  • New Zealand
  • Nutrition Policy
  • Nutritional Status
  • Patient Education as Topic
  • Selenium / deficiency*
  • Vitamin E Deficiency / complications*
  • Zinc / deficiency*

Substances

  • Selenium
  • Zinc
  • Calcium