Percutaneous vertebroplasty treatment of steroid-induced osteoporotic compression fractures

Arthritis Rheum. 1998 Jan;41(1):171-5. doi: 10.1002/1529-0131(199801)41:1<171::AID-ART21>3.0.CO;2-5.


This report describes the case of a woman in whom multiple compression fractures of the lower thoracic and lumbar spine occurred in association with long-term corticosteroid therapy for systemic lupus erythematosus. Pain markedly limited the patient's mobility and daily activities, and conservative therapy with bracing and narcotic analgesics gave little improvement. Affected vertebrae were treated with polymethylmethacrylate, introduced percutaneously under fluoroscopic guidance. The resulting reinforcement of the fractured vertebral bodies eliminated the pain and the need for narcotic analgesics. The utilization of percutaneous verterbroplasty as a therapeutic alternative for the treatment of pain resulting from osteoporotic compression fractures is described.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fractures, Spontaneous / diagnostic imaging
  • Fractures, Spontaneous / etiology
  • Fractures, Spontaneous / therapy*
  • Humans
  • Lumbar Vertebrae / blood supply
  • Lumbar Vertebrae / pathology
  • Lumbar Vertebrae / surgery
  • Lupus Erythematosus, Systemic / drug therapy*
  • Osteoporosis / chemically induced
  • Osteoporosis / complications*
  • Pain Management
  • Phlebography
  • Polymethyl Methacrylate / therapeutic use
  • Spinal Fractures / diagnostic imaging
  • Spinal Fractures / etiology
  • Spinal Fractures / therapy*
  • Steroids / adverse effects*
  • Thoracic Vertebrae / blood supply
  • Thoracic Vertebrae / pathology
  • Thoracic Vertebrae / surgery


  • Steroids
  • Polymethyl Methacrylate