Interleukin 18, a cytokine which resembles IL-1 structurally and IL-12 functionally but exerts its effect independently of both

Clin Immunol Immunopathol. 1998 Jan;86(1):11-5. doi: 10.1006/clin.1997.4475.
No abstract available

Publication types

  • Review

MeSH terms

  • Adrenal Glands / metabolism
  • Animals
  • COS Cells
  • Colonic Neoplasms / therapy
  • Cytokines / chemistry
  • Cytokines / pharmacology
  • Cytokines / physiology*
  • Cytokines / therapeutic use
  • Humans
  • Immunologic Factors / therapeutic use
  • Interferon-gamma / biosynthesis
  • Interleukin-18
  • Interleukin-18 Receptor alpha Subunit
  • Killer Cells, Natural / drug effects
  • Kupffer Cells / metabolism
  • Mice
  • Mice, Inbred BALB C
  • Receptors, Interleukin / physiology
  • Receptors, Interleukin-18
  • Recombinant Fusion Proteins / metabolism
  • Signal Transduction
  • T-Lymphocytes / drug effects
  • Transfection
  • Tumor Cells, Cultured

Substances

  • Cytokines
  • IL18R1 protein, human
  • Il18r1 protein, mouse
  • Immunologic Factors
  • Interleukin-18
  • Interleukin-18 Receptor alpha Subunit
  • Receptors, Interleukin
  • Receptors, Interleukin-18
  • Recombinant Fusion Proteins
  • Interferon-gamma