Antifreeze proteins

Curr Opin Struct Biol. 1997 Dec;7(6):828-34. doi: 10.1016/s0959-440x(97)80154-6.


Antifreeze proteins comprise a structurally diverse class of proteins that inhibit the growth of ice. Recently, new AFP types have been discovered; more active AFPs have been isolated; antecedents have been recognized supporting the notion of recent, multiple origins; and detailed structures have emerged leading to models for their adsorption to ice.

Publication types

  • Review

MeSH terms

  • Animals
  • Antifreeze Proteins
  • Crystallography, X-Ray
  • Fishes
  • Glycoproteins / chemistry*
  • Glycoproteins / classification
  • Glycoproteins / metabolism
  • Ice
  • Insect Proteins / chemistry
  • Models, Molecular
  • Protein Binding
  • Protein Conformation*
  • Protein Structure, Secondary
  • Protein Structure, Tertiary


  • Antifreeze Proteins
  • Glycoproteins
  • Ice
  • Insect Proteins