Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery

J Med Chem. 1997 Dec 19;40(26):4169-94. doi: 10.1021/jm970377o.

Publication types

  • Review

MeSH terms

  • Acetylcholine / metabolism
  • Animals
  • Binding Sites
  • Dopamine / metabolism
  • Drug Design
  • Humans
  • Molecular Structure
  • Nervous System / drug effects
  • Nervous System / metabolism*
  • Neurons / chemistry*
  • Nicotine / metabolism
  • Nicotine / pharmacology*
  • Nicotinic Agonists / chemistry
  • Nicotinic Agonists / pharmacology*
  • Nicotinic Antagonists / chemistry
  • Nicotinic Antagonists / pharmacology*
  • Receptors, Nicotinic / chemistry
  • Receptors, Nicotinic / classification
  • Receptors, Nicotinic / metabolism*
  • Structure-Activity Relationship

Substances

  • Nicotinic Agonists
  • Nicotinic Antagonists
  • Receptors, Nicotinic
  • Nicotine
  • Acetylcholine
  • Dopamine