Congenital syphilis after maternal treatment with erythromycin

Obstet Gynecol. 1976 Apr;47(4):492-4.


A case is reported in which erythromycin was used successfully to treat maternal syphilis but failed to adequately treat the fetus. This report and similar studies suggest that oral erythromycin is not a reasonable alternative drug for the treatment of lues in the penicillin-allergic gravid female.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Erythromycin / therapeutic use*
  • Female
  • Humans
  • Infant
  • Penicillin G Procaine / therapeutic use
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy*
  • Syphilis, Congenital / drug therapy*


  • Penicillin G Procaine
  • Erythromycin