The Kluver-Bucy syndrome

J Neurosurg Sci. 1997 Sep;41(3):269-72.


Evolution of psychological disorders following head injury including memory disorders and other cognitive ones are common. The best known are psychiatric disturbances of various kind after lesions of frontal lobes. Cognitive, behavioural and emotional disorders are not usually seen in patients with bilateral temporal lesions. In our Department of Neurotraumatology we observed 4 patients with post-traumatic lesions localized bitemporally. They developed Kluver-Bucy syndrome--rarity in human pathology--with combination of three or more the following syndromes: increased oral activity, hypersexuality, hypermetamorphosis, memory disorders, placidity, loss of people recognition, bulimia. Several symptoms responded dramatically to carbamazepine. We conclude that it may be a useful agent in treatment of this unusual syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Agnosia / diagnosis*
  • Animals
  • Brain Damage, Chronic / diagnosis*
  • Feeding Behavior / physiology*
  • Humans
  • Learning / physiology
  • Macaca mulatta
  • Male
  • Memory Disorders / diagnosis*
  • Sexual Behavior / physiology*
  • Syndrome
  • Temporal Lobe / injuries*
  • Tomography, X-Ray Computed