[Programmed cell death (apoptosis): molecular mechanisms and the role in biology and medicine]

Vopr Med Khim. 1997 Sep-Oct;43(5):402-16.
[Article in Russian]

Abstract

Over the recent years studies of the cell death (CD) were progressing with an outstanding speed. CD is found to play a key role in proliferation, differentiation, embryogenesis, morphogenesis and homeostatic processes. CD abnormalities significantly contribute into numerous human diseases as cancer, AIDS, degenerative pathologies of nervous system and developmental abnormalities. The elucidation of CD mechanisms may promote our understanding of pathogenesis of various diseases and facilitate search for their treatment.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Apoptosis* / genetics
  • Apoptosis* / physiology
  • Gene Expression Regulation
  • Humans
  • Lipid Peroxidation
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / physiology

Substances

  • Receptors, Cell Surface