Salmon calcitonin induced hypocalcemia and hyperphosphatemia in an elasmobranch, Dasyatis akajei

Gen Comp Endocrinol. 1998 Jan;109(1):8-12. doi: 10.1006/gcen.1997.6997.

Abstract

Salmon calcitonin (5 micrograms/kg body wt) was administered in an elasmobranch, Dasyatis akajei, to investigate the effects upon plasma calcium and inorganic phosphate. The hormone produced hypocalcemia and hyperphosphatemia in the stingray. It is concluded that calcitonin may have a role in calcium homeostasis by a mechanism different from that on bones.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calcitonin / administration & dosage
  • Calcitonin / physiology
  • Calcitonin / toxicity*
  • Calcium / blood*
  • Calcium / metabolism
  • Cohort Studies
  • Elasmobranchii / blood*
  • Elasmobranchii / metabolism
  • Female
  • Homeostasis
  • Hypocalcemia / blood
  • Hypocalcemia / chemically induced*
  • Hypocalcemia / metabolism
  • Injections, Intraperitoneal
  • Male
  • Phosphates / blood*
  • Phosphates / metabolism
  • Salmon
  • Time Factors

Substances

  • Phosphates
  • salmon calcitonin
  • Calcitonin
  • Calcium